'<' not supported between instances of 'str' and 'int'

[jayaherkar]

import random

secret = random.randint(1, 99)
guess = 0
tries = 0
print("AHOY! I'm the Dread Pirate Roberts, and I have a secret")
print("It's the number from 1 to 99..and I'll give you 6 chances")

while guess != secret and tries < 6:
    guess = input("What's your guess? ")
    if guess < secret:
        print("To Low...You creep")

    elif guess > secret:
        print("Too High, Douchbag")
        tries = tries + 1

        if guess == secret:
            print("Avast! You finally got it!")

        else:
            print("No more chances...Play again later")
            print("The secret number was", secret)

[perfringo]

input returns string and therefore you comparing string with int which for quite obvious reasons is not possible. You should convert input to int.